Examining the cognitive effects of a special extract of Bacopa monniera (CDRI08: Keenmnd): a review of ten years of research at Swinburne University

J Pharm Pharm Sci. 2013;16(2):254-8. doi: 10.18433/j35g6m.


Bacopa monniera (EBm), an Indian aquatic herb, has been used in traditional Ayurvedic medicine for centuries for indications related to memory and inflammation. More recently specific extracts of EBm have emerged that have been subjected to rigorous in vitro, animal and now human clinical trials. In this paper we discuss some of these studies with special reference to mechanisms and efficacy of a special extract of Bacopa (CDRI08). Studies using this extract indicate that CDRI08 has several modes of action on the human brain. Promising indications for use in humans include improving cognition in the elderly and in patients with neurodegenerative disorders.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Australia
  • Bacopa*
  • Cognition / drug effects
  • Humans
  • Nootropic Agents / pharmacology*
  • Plant Extracts / pharmacology*
  • Universities


  • Nootropic Agents
  • Plant Extracts