Phytochemical and biological studies of Adiantum capillus-veneris L
- PMID: 23960744
- PMCID: PMC3745073
- DOI: 10.1016/j.jsps.2011.01.007
Phytochemical and biological studies of Adiantum capillus-veneris L
Abstract
Chromatographic fractionation of the alcoholic extract of the dried fronds of Adiantum capillus-veneris L. (Adiantaceae) yielded seven compounds: four triterpenoidal compounds belonging to adiantane and filicane groups were isolated from the hexane fraction and identified as isoadiantone (1); isoadiantol-B (2); 3-methoxy-4-hydroxyfilicane (3) and 3,4-dihydroxyfilicane (4) and three flavonoids were isolated from the ethyl acetate fraction and identified as: quercetin (5), quercetin-3-O-glucoside (6) and quercetin-3-O-rutinoside (rutin) (7). The identification of the isolated compounds has been established through their physical, chemical and spectroscopic methods including IR, (1)H NMR, (13)C NMR, HSQC, HMBC, NOESY and MS. Biological studies of the total alcoholic extract, hexane fraction and some of the isolated compounds showed an anti-inflammatory activity while the hypoglycemic study of the total alcoholic extract showed a significant activity.
Keywords: Adiantane; Adiantum capillus-veneris L.; Anti-inflammatory; Filicane triterpenoids; Flavonoids; Hypoglycemic.
Figures
Similar articles
-
Anti-inflammatory and anti-nociceptive activities of two new triterpenoids from Adiantum capillus-veneris Linn.Nat Prod Res. 2013;27(24):2304-10. doi: 10.1080/14786419.2013.828292. Epub 2013 Aug 25. Nat Prod Res. 2013. PMID: 23972143
-
Antiobesity and antihyperglycaemic effects of Adiantum capillus-veneris extracts: in vitro and in vivo evaluations.Pharm Biol. 2017 Dec;55(1):164-172. doi: 10.1080/13880209.2016.1233567. Epub 2016 Sep 23. Pharm Biol. 2017. PMID: 27663206 Free PMC article.
-
In vitro phytochemical, antibacterial, and antifungal activities of leaf, stem, and root extracts of Adiantum capillus veneris.ScientificWorldJournal. 2014 Jan 28;2014:269793. doi: 10.1155/2014/269793. eCollection 2014. ScientificWorldJournal. 2014. PMID: 24592156 Free PMC article.
-
A Review of Pharmacological Properties and Toxicological Effects of Adiantum capillus-veneris L.Curr Drug Discov Technol. 2021;18(2):186-193. doi: 10.2174/1570163817666200316111445. Curr Drug Discov Technol. 2021. PMID: 32178614 Review.
-
Medicinal Properties of Adiantum capillus-veneris Linn. in Traditional Medicine and Modern Phytotherapy: A Review Article.Iran J Public Health. 2018 Feb;47(2):188-197. Iran J Public Health. 2018. PMID: 29445628 Free PMC article. Review.
Cited by
-
Mitigation of Hepatotoxicity via Boosting Antioxidants and Reducing Oxidative Stress and Inflammation in Carbendazim-Treated Rats Using Adiantum Capillus-Veneris L. Extract.Molecules. 2023 Jun 12;28(12):4720. doi: 10.3390/molecules28124720. Molecules. 2023. PMID: 37375275 Free PMC article.
-
Aqueous Ethanolic Extract of Adiantum incisum Forssk. Protects against Type 2 Diabetes Mellitus via Attenuation of α-Amylase and Oxidative Stress.ACS Omega. 2022 Oct 12;7(42):37724-37735. doi: 10.1021/acsomega.2c04673. eCollection 2022 Oct 25. ACS Omega. 2022. PMID: 36312418 Free PMC article.
-
Anti-Inflammatory and Antimicrobial Activity of Silver Nanoparticles Green-Synthesized Using Extracts of Different Plants.Nanomaterials (Basel). 2024 Aug 25;14(17):1383. doi: 10.3390/nano14171383. Nanomaterials (Basel). 2024. PMID: 39269046 Free PMC article.
-
Types of headache and those remedies in traditional persian medicine.Pharmacogn Rev. 2013 Jan;7(13):17-26. doi: 10.4103/0973-7847.112835. Pharmacogn Rev. 2013. PMID: 23922452 Free PMC article.
-
Effect of Adiantum Capillus veneris Linn on an Animal Model of Testosterone-Induced Hair Loss.Iran J Pharm Res. 2014 Winter;13(Suppl):113-8. Iran J Pharm Res. 2014. PMID: 24711836 Free PMC article.
References
-
- Abbasi A.M., Khan M.A., Ahmad M., Zafar M., Jahan S., Sultana S. Ethnopharmacological application of medicinal plants to cure skin diseases and in folk cosmetics among the tribal communities of North-West Frontier Province, Pakistan. J. Ethnopharmacol. 2010;128:322–335. - PubMed
-
- Abbasi M., Khan M.A., Ahmad M., Zafar M., Khan H., Muhammad N., Sultana S. Medicinal plants used for the treatment of jaundice and hepatitis based on socio-economic documentation. Afr. J. Biotechnol. 2009;8:1643–1650.
-
- Abdel-Halim O.B., Ibraheim Z.Z., Shiojima K. Oleanane triterpenes from Adiantum capillus-veneris growing in Egypt. Alex. J. Pharm. Sci. 2002;16:87–92.
-
- Ahmad I., Hussain M., Ahmad M.S.A., Ashraf M.Y., Ahmad R., Ali A. Spatio-temporal variations in physiochemical attributes of Adiantum capillus-veneris from Soone valley of salt range (Pakistan) Pak. J. Bot. 2008;40:1387–1398.
-
- Al-Qura’n S. Ethnopharmacological survey of wild medicinal plants in Showbak, Jordan. J. Ethnopharmacol. 2009;123:45–50. - PubMed
LinkOut - more resources
Full Text Sources
Other Literature Sources
) of compound 4.
