Phytochemical and biological studies of Adiantum capillus-veneris L
- PMID: 23960744
- PMCID: PMC3745073
- DOI: 10.1016/j.jsps.2011.01.007
Phytochemical and biological studies of Adiantum capillus-veneris L
Abstract
Chromatographic fractionation of the alcoholic extract of the dried fronds of Adiantum capillus-veneris L. (Adiantaceae) yielded seven compounds: four triterpenoidal compounds belonging to adiantane and filicane groups were isolated from the hexane fraction and identified as isoadiantone (1); isoadiantol-B (2); 3-methoxy-4-hydroxyfilicane (3) and 3,4-dihydroxyfilicane (4) and three flavonoids were isolated from the ethyl acetate fraction and identified as: quercetin (5), quercetin-3-O-glucoside (6) and quercetin-3-O-rutinoside (rutin) (7). The identification of the isolated compounds has been established through their physical, chemical and spectroscopic methods including IR, (1)H NMR, (13)C NMR, HSQC, HMBC, NOESY and MS. Biological studies of the total alcoholic extract, hexane fraction and some of the isolated compounds showed an anti-inflammatory activity while the hypoglycemic study of the total alcoholic extract showed a significant activity.
Keywords: Adiantane; Adiantum capillus-veneris L.; Anti-inflammatory; Filicane triterpenoids; Flavonoids; Hypoglycemic.
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References
-
- Abbasi A.M., Khan M.A., Ahmad M., Zafar M., Jahan S., Sultana S. Ethnopharmacological application of medicinal plants to cure skin diseases and in folk cosmetics among the tribal communities of North-West Frontier Province, Pakistan. J. Ethnopharmacol. 2010;128:322–335. - PubMed
-
- Abbasi M., Khan M.A., Ahmad M., Zafar M., Khan H., Muhammad N., Sultana S. Medicinal plants used for the treatment of jaundice and hepatitis based on socio-economic documentation. Afr. J. Biotechnol. 2009;8:1643–1650.
-
- Abdel-Halim O.B., Ibraheim Z.Z., Shiojima K. Oleanane triterpenes from Adiantum capillus-veneris growing in Egypt. Alex. J. Pharm. Sci. 2002;16:87–92.
-
- Ahmad I., Hussain M., Ahmad M.S.A., Ashraf M.Y., Ahmad R., Ali A. Spatio-temporal variations in physiochemical attributes of Adiantum capillus-veneris from Soone valley of salt range (Pakistan) Pak. J. Bot. 2008;40:1387–1398.
-
- Al-Qura’n S. Ethnopharmacological survey of wild medicinal plants in Showbak, Jordan. J. Ethnopharmacol. 2009;123:45–50. - PubMed
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