Benznidazole treatment of chagasic encephalitis in pregnant woman with AIDS

Emerg Infect Dis. 2013;19(9):1490-2. doi: 10.3201/eid1909.130667.


We report a case of chagasic meningoencephalitis reactivation in a pregnant woman co-infected with Trypanosoma cruzi and HIV that was successfully managed with benznidazole and highly active antiretroviral therapy. Early diagnosis enabled rapid specific treatment that improved the health of the patient and her baby.

Keywords: AIDS; Chagas disease reactivation; HIV; Trypanosoma cruzi; benznidazole; parasites; pregnancy; protozoa.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acquired Immunodeficiency Syndrome* / drug therapy
  • Adult
  • Antiretroviral Therapy, Highly Active
  • Chagas Disease / drug therapy*
  • Coinfection
  • Encephalitis / drug therapy*
  • Female
  • Humans
  • Infant, Newborn
  • Nitroimidazoles / therapeutic use*
  • Pregnancy
  • Pregnancy Complications, Infectious*
  • Pregnancy Outcome
  • Treatment Outcome
  • Trypanocidal Agents / therapeutic use*
  • Trypanosoma cruzi / genetics


  • Nitroimidazoles
  • Trypanocidal Agents
  • benzonidazole