Macrolide-resistant Mycoplasma Pneumoniae in Humans, Ontario, Canada, 2010-2011

Emerg Infect Dis. 2013;19(9):1525-1527. doi: 10.3201/eid1909.121466.

Abstract

Antimicrobial drug resistance rates for Mycoplasma pneumoniae was determined in clinical specimens and isolates obtained during 2011-2012 in Ontario, Canada. Of 91 M. pneumoniae drug-resistant specimens, 11 (12.1%) carried nucleotide mutations associated with macrolide resistance in the 23S rRNA gene. None of the M. pneumoniae specimens were resistant to fluoroquinolones or tetracyclines.

Keywords: Canada; Mycoplasma pneumoniae; Ontario; antibiotic resistance; antimicrobial resistance; bacteria; community-acquired pneumonia; macrolide resistance; macrolides.

MeSH terms

  • Adolescent
  • Adult
  • Anti-Bacterial Agents / pharmacology*
  • Anti-Bacterial Agents / therapeutic use
  • Child
  • Child, Preschool
  • Drug Resistance, Bacterial*
  • Genes, Bacterial
  • Genotype
  • Humans
  • Macrolides / pharmacology*
  • Macrolides / therapeutic use
  • Multilocus Sequence Typing
  • Mycoplasma pneumoniae / drug effects*
  • Mycoplasma pneumoniae / genetics
  • Ontario / epidemiology
  • Pneumonia, Mycoplasma / drug therapy
  • Pneumonia, Mycoplasma / epidemiology*
  • Young Adult

Substances

  • Anti-Bacterial Agents
  • Macrolides