Abstract
In this issue of Blood, Ghosh and colleagues report that knocking out an inositol kinase in mice diminishes polyphosphate in platelet dense granules, thereby reducing hemostasis and protecting against thrombosis.
MeSH terms
-
Animals
-
Blood Platelets / metabolism*
-
Male
-
Phosphotransferases (Phosphate Group Acceptor) / physiology*
-
Polyphosphates / metabolism*
Substances
-
Polyphosphates
-
Phosphotransferases (Phosphate Group Acceptor)
-
inositol hexakisphosphate kinase