A new signaling paradigm to control the prenylation and trafficking of small GTPases

Carol L Williams

doi:10.4161/cc.26230

A new signaling paradigm to control the prenylation and trafficking of small GTPases

Cell Cycle. 2013;12(18):2933-4. doi: 10.4161/cc.26230. Epub 2013 Aug 23.

Author

Carol L Williams¹

Affiliation

¹ Department of Pharmacology and Toxicology; Cancer Center and Cardiovascular Center; Medical College of Wisconsin; Milwaukee, WI USA.

No abstract available

Keywords: ADORA2B; K-Ras; Rap1; Rap1GDS1; RhoA; SmgGDS; adenosine; adenosine A2B receptor; cancer; isoprenylation; localization; metastasis; polybasic region; trafficking.

Publication types

Editorial
Comment

MeSH terms

Adenosine / metabolism*
Animals
Cell Movement / physiology*
Humans
Models, Biological*
Neoplasm Metastasis / physiopathology*
Signal Transduction / physiology*
Tumor Microenvironment*
rap GTP-Binding Proteins / metabolism*

Substances

rap GTP-Binding Proteins
Adenosine

Grants and funding

R01 CA136799/CA/NCI NIH HHS/United States