Alopecia areata: an update

Indian J Dermatol Venereol Leprol. Sep-Oct 2013;79(5):563-75. doi: 10.4103/0378-6323.116725.

Abstract

Alopecia areata (AA) is a common form of non-scarring hair loss of scalp and/or body. Genetic predisposition, autoimmunity, and environmental factors play a major role in the etiopathogenesis of AA. Patchy AA is the most common form. Atopy and autoimmune thyroiditis are most common associated conditions. Peribulbar and intrabulbar lymphocytic inflammatory infiltrate resembling "swarm of bees" is characteristic on histopathology. Treatment is mainly focused to contain the disease activity. Corticosteroids are the preferred treatments in form of topical, intralesional, or systemic therapy. Camouflage in the form of wigs may be an alternative option in refractory cases.

Publication types

  • Review

MeSH terms

  • Adrenal Cortex Hormones / therapeutic use*
  • Alopecia Areata / drug therapy*
  • Alopecia Areata / etiology*
  • Alopecia Areata / physiopathology*
  • Humans
  • Scalp / pathology*

Substances

  • Adrenal Cortex Hormones