[Curative effects of modified xiao-jin pills and chemotherapy after surgery in patients with mid and late phase gastric cancer]

Zhong Xi Yi Jie He Za Zhi. 1990 Jun;10(6):343-4, 324.
[Article in Chinese]


From 1986, the authors mainly used Modified Xiao-Jin Pills (MXJP) added with chemical treatment to cure patients in mid and late phase of gastric cancer after operation. 72 patients were verified as gastric cancer by pathological section and phases were divided according to TNM classification which was revised by the national cooperative group of gastric cancer in 1978. The patients were randomly divided into curative and control groups. The two groups were basically similar in sex, age, clinic pathological phase and operation. One month after operation, the two groups received the same treatment except that the control group did not take MXJP. The indexes of observation consisted of living rate, substance of tongue and 5 indexes of blood coagulation (AT-III, Fn, FA, VIII R:Ag and beta TG). The curative effects showed that MXJP could enhance gastric cancer patients living rate for 1, 1.5 and 2 years among which it was obvious for phase IV's gastric cancer patients to enhance 1 year's living rate (P less than 0.05), and lower the negative rate of substance of tongue (P less than 0.001). The indexes of AT-III, Fn FA and VIII R:Ag and beta TG of gastric cancer patients had changed for the better (P less than 0.05). The results showed that MXJP can enhance the capacity of body to antagonize coagulation fibrinolysis, remove blood stasis and further enhance the living rate of patients. MXJP has better curative effects of short term.

Publication types

  • Clinical Trial
  • English Abstract
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Aged
  • Blood Coagulation
  • Drugs, Chinese Herbal / therapeutic use*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Postoperative Period
  • Stomach Neoplasms / blood
  • Stomach Neoplasms / drug therapy*
  • Stomach Neoplasms / mortality
  • Survival Rate
  • Tongue / pathology


  • Drugs, Chinese Herbal