Assignment of the vascular smooth muscle actin gene ACTSA to human chromosome 10

Jinrui Idengaku Zasshi. 1990 Jun;35(2):145-50. doi: 10.1007/BF01876459.

Abstract

Human vascular smooth muscle actin gene (ACTSA) was cloned and its unique sequence was used as the hybridization probe for Southern blot analysis of DNAs from 18 rodent-human somatic cell hybrids; the gene was assigned to human chromosome 10. Regional mapping by in situ hybridization showed that the gene is located on the long arm (q22-q24) of the chromosome. Thus, the gene is on a different chromosome from the other four actin genes so far examined.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Actins / genetics*
  • Chromosomes, Human, Pair 10*
  • Cloning, Molecular
  • DNA Probes
  • Humans
  • Muscle, Smooth / ultrastructure*
  • Restriction Mapping

Substances

  • Actins
  • DNA Probes