Microwave radiation induced oxidative stress, cognitive impairment and inflammation in brain of Fischer rats

Indian J Exp Biol. 2012 Dec;50(12):889-96.

Abstract

Public concerns over possible adverse effects of microwave radiation emitted by mobile phones on health are increasing. To evaluate the intensity of oxidative stress, cognitive impairment and inflammation in brain of Fischer rats exposed to microwave radiation, male Fischer-344 rats were exposed to 900 MHz microwave radiation (SAR = 5.953 x 10(-4) W/kg) and 1800 MHz microwave radiation (SAR = 5.835 x 10(-4) W/kg) for 30 days (2 h/day). Significant impairment in cognitive function and induction of oxidative stress in brain tissues of microwave exposed rats were observed in comparison with sham exposed groups. Further, significant increase in level of cytokines (IL-6 and TNF-alpha) was also observed following microwave exposure. Results of the present study indicated that increased oxidative stress due to microwave exposure may contribute to cognitive impairment and inflammation in brain.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cognition Disorders / blood
  • Cognition Disorders / etiology*
  • Dose-Response Relationship, Radiation
  • Encephalitis / blood
  • Encephalitis / etiology*
  • Free Radicals
  • Interleukin-6 / blood
  • Male
  • Maze Learning / radiation effects
  • Microwaves / adverse effects*
  • Oxidative Stress / radiation effects*
  • Radiation Injuries, Experimental / blood
  • Radiation Injuries, Experimental / etiology*
  • Random Allocation
  • Rats
  • Rats, Inbred F344
  • Tumor Necrosis Factor-alpha / blood

Substances

  • Free Radicals
  • Interleukin-6
  • Tumor Necrosis Factor-alpha