Bilateral secondary neurolymphomatosis of the internal auditory canal nerves: a case report

Am J Otolaryngol. 2013 Sep-Oct;34(5):556-8. doi: 10.1016/j.amjoto.2013.04.002. Epub 2013 May 8.

Abstract

Background: Neurolymphomatosis describes the malignant lymphomatous infiltration of nerves.

Methods: We encountered a unique case of a 47-year-old patient with non-Hodgkin's lymphoma presenting with bilateral sensorineural hearing loss, vestibular dysfunction and bilateral facial nerve palsy.

Results: Magnetic resonance imaging demonstrated enhancement and thickening of internal auditory canal nerves bilaterally consistent with neurolymphomatosis. Patient was treated with combined intrathecal chemotherapy and total brain irradiation.

Conclusions: One must always remain vigilant for metastatic disease in patients with sensorineural hearing loss and/or vestibular dysfunction and facial nerve palsy in the context of known malignancy.

Publication types

  • Case Reports

MeSH terms

  • Cochlear Nerve / pathology*
  • Combined Modality Therapy
  • Diagnosis, Differential
  • Ear, Inner / pathology*
  • Hearing Loss, Sensorineural / diagnosis
  • Hearing Loss, Sensorineural / etiology*
  • Hearing Loss, Sensorineural / therapy
  • Humans
  • Lymphoma, Follicular / complications
  • Lymphoma, Follicular / diagnosis
  • Lymphoma, Follicular / pathology*
  • Magnetic Resonance Imaging / methods
  • Male
  • Middle Aged
  • Nervous System Neoplasms / complications
  • Nervous System Neoplasms / diagnosis
  • Nervous System Neoplasms / pathology*