Personalized network-based treatments in oncology

Clin Pharmacol Ther. 2013 Dec;94(6):646-50. doi: 10.1038/clpt.2013.171. Epub 2013 Aug 29.


Network medicine aims at unraveling cell signaling networks to propose personalized treatments for patients suffering from complex diseases. In this short review, we show the relevance of network medicine to cancer treatment by outlining the potential convergence points of the most recent technological and scientific developments in both drug design and signaling network analysis.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Antineoplastic Combined Chemotherapy Protocols / pharmacology
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Biomarkers / metabolism
  • Drug Design*
  • Humans
  • Molecular Targeted Therapy*
  • Neoplasms / drug therapy*
  • Neoplasms / metabolism
  • Precision Medicine / methods*
  • Protein Interaction Maps
  • Protein Processing, Post-Translational
  • Signal Transduction
  • Systems Biology


  • Biomarkers