Urinary phenylacetic acid in panic disorder with and without depression

Acta Psychiatr Scand. 1990 Jul;82(1):14-6. doi: 10.1111/j.1600-0447.1990.tb01347.x.

Abstract

Phenylacetic acid (PAA) excretion was measured in 39 patients who met criteria for panic disorder; 9 of these also had major depression, and 30 did not. Patients with panic and depression excreted 66 +/- 23 mg/day of PAA, an amount significantly lower than in normal controls; patients with panic disorder but without depression excreted 104 +/- 23 mg/day of PAA (not significantly lower than controls). The results support previous studies indicating that PAA excretion is a marker for depressive disorder.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Anxiety Disorders / diagnosis
  • Anxiety Disorders / urine*
  • Depressive Disorder / diagnosis
  • Depressive Disorder / urine*
  • Fear / physiology*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Panic / physiology*
  • Phenylacetates / urine*

Substances

  • Phenylacetates
  • phenylacetic acid