Anterior uveitis and cataract after rubella vaccination: a case report of a 12-month-old girl

Pediatrics. 2013 Oct;132(4):e1035-8. doi: 10.1542/peds.2012-2930. Epub 2013 Sep 2.


Many reports associating uveitis after vaccination have been reported, including 2 cases after measles, mumps, and rubella (MMR) vaccine. We report the case of a 12-month-old girl who developed a unilateral anterior uveitis with rubeosis and cataract 3 months after an MMR vaccination at 9 months of age. Aqueous humor analysis showed the presence of more rubella-specific immunoglobulin G in the affected eye than in the unaffected one. This is the second report showing an association between MMR vaccine and anterior uveitis and the first supported by the presence of intraocular rubella antibodies.

Keywords: cataract; rubella vaccine; uveitis.

Publication types

  • Case Reports

MeSH terms

  • Antibodies, Viral / blood
  • Cataract / blood
  • Cataract / chemically induced*
  • Cataract / diagnosis*
  • Female
  • Humans
  • Infant
  • Measles-Mumps-Rubella Vaccine / adverse effects*
  • Uveitis, Anterior / blood
  • Uveitis, Anterior / chemically induced*
  • Uveitis, Anterior / diagnosis*


  • Antibodies, Viral
  • Measles-Mumps-Rubella Vaccine
  • rubella antibodies