Pseudomonas cepacia: a new pathogen in patients with cystic fibrosis referred to a large centre in the United Kingdom

Arch Dis Child. 1990 Aug;65(8):874-7. doi: 10.1136/adc.65.8.874.


Pseudomonas cepacia infection has become increasingly common among patients with cystic fibrosis in North America. In a large cystic fibrosis centre in the United Kingdom 11 cases have been identified during the last six years, with a maximum prevalence of 7% in 1988. Three patients have died, two of whom deteriorated rapidly shortly after acquisition of the organism despite intensive treatment with appropriate antibiotics. Analysis of possible causes of the increase in P cepacia infection suggested that neither patient to patient transmission nor the use of nebulised antibiotics was associated with an increased risk of infection.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Anti-Bacterial Agents / administration & dosage
  • Child
  • Child, Preschool
  • Cross Infection
  • Cystic Fibrosis / complications*
  • England / epidemiology
  • Female
  • Humans
  • Infant
  • Male
  • Nebulizers and Vaporizers
  • Pseudomonas Infections / epidemiology*
  • Pseudomonas Infections / etiology
  • Retrospective Studies
  • Risk Factors


  • Anti-Bacterial Agents