Renal cell carcinoma in pregnancy: a rare coexistence

Clin Transl Oncol. 2014 Feb;16(2):122-7. doi: 10.1007/s12094-013-1105-2. Epub 2013 Sep 4.


Renal cell carcinoma (RCC) is rarely diagnosed during pregnancy and its management represents a real challenge. As the symptomatology might mimic other common pregnancy-related disorders, the diagnosis is often delayed. RCC should be considered in women of childbearing age who present with recurrent or refractory urinary tract symptoms, flank pain, or a palpable mass. Ultrasound appears to be the imaging procedure of choice followed by the magnetic resonance imaging for evaluating the urinary system in pregnant women. The probability of cure is directly related to the stage or degree of tumor dissemination. Surgical resection is the mainstay of treatment.

Publication types

  • Review

MeSH terms

  • Carcinoma, Renal Cell / complications*
  • Carcinoma, Renal Cell / diagnosis
  • Carcinoma, Renal Cell / epidemiology*
  • Carcinoma, Renal Cell / therapy
  • Female
  • Humans
  • Incidence
  • Kidney Neoplasms / complications*
  • Kidney Neoplasms / diagnosis
  • Kidney Neoplasms / epidemiology*
  • Kidney Neoplasms / therapy
  • Magnetic Resonance Imaging
  • Pregnancy
  • Pregnancy Complications, Neoplastic / diagnosis
  • Pregnancy Complications, Neoplastic / epidemiology*
  • Pregnancy Complications, Neoplastic / therapy