Determination of 2,6-dimethyl-4-(2'-nitrosophenyl)-3,5-pyridinedicarboxylic acid dimethylester in nifedipine by derivative UV-spectrophotometry in bulk material and pharmaceutical forms

G Carlucci; A Colanzi; P Mazzeo

Determination of 2,6-dimethyl-4-(2'-nitrosophenyl)-3,5-pyridinedicarboxylic acid dimethylester in nifedipine by derivative UV-spectrophotometry in bulk material and pharmaceutical forms

Farmaco. 1990 Jun;45(6 Suppl):751-5.

Authors

G Carlucci¹, A Colanzi, P Mazzeo

Affiliation

¹ Dipartimento di Chimica, Università dell'Aquila, Italy.

PMID: 2400525

Abstract

A method for the determination of 2,6-dimethyl-4-(2'-nitrosophenyl)-3,5-pyridinedicarboxylic acid dimethylester in nifedipine (bulk material and pharmaceutical formulations) by second-derivative ultraviolet spectrophotometry is described. The procedure is simple and rapid and gives accurate and precise results.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Dihydropyridines / analysis*
Indicators and Reagents
Nifedipine / analysis*
Solutions
Spectrophotometry, Ultraviolet
Tablets

Substances

Dihydropyridines
Indicators and Reagents
Solutions
Tablets
2,6-dimethyl-4-(2'-nitrosophenyl)-3,5-pyridinedicarboxylic acid dimethyl ester
Nifedipine