Negative-pressure wound therapy with instillation: international consensus guidelines

Plast Reconstr Surg. 2013 Dec;132(6):1569-1579. doi: 10.1097/PRS.0b013e3182a80586.


Background: Negative-pressure wound therapy with instillation is increasingly utilized as an adjunct therapy for a wide variety of wounds. Despite its growing popularity, there is a paucity of evidence and lack of guidance to provide effective use of this therapy.

Methods: A panel of experts was convened to provide guidance regarding the appropriate use of negative-pressure wound therapy with instillation. A face-to-face meeting was held where the available evidence was discussed and individual clinical experience with this therapy was shared. Follow-up communication among the panelists continued until consensus was achieved. The final consensus recommendations were derived through more than 80 percent agreement among the panelists.

Results: Nine consensus statements were generated that address the appropriate use of negative-pressure wound therapy with instillation. The question of clinical effectiveness of this therapy was not directly addressed by the consensus panel.

Conclusion: This document serves as preliminary guidelines until more robust evidence emerges that will support or modify these consensus recommendations.

Publication types

  • Consensus Development Conference
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Consensus
  • Evidence-Based Medicine
  • Humans
  • Negative-Pressure Wound Therapy / methods*
  • Negative-Pressure Wound Therapy / standards*
  • Practice Guidelines as Topic*
  • Wound Healing*
  • Wounds and Injuries / therapy*