[Physical activity and cancer survival]

Bull Cancer. 2012 Oct;99(10):979-94. doi: 10.1684/bdc.2012.1648.
[Article in French]

Abstract

Physical activity has been shown in large cohort studies to positively impact survival in cancer survivors. Existing randomized controlled trials showed a beneficial effect of physical activity on physical fitness, quality of life, anxiety and self-esteem; however, the small sample size, the short follow-up and the lack of standardization of physical activity intervention across studies impaired definite conclusion in terms of survival. Physical activity reduces adiposity and circulating estrogen levels and increases insulin sensitivity among other effects. A workshop was conducted at the International Agency for Research on Cancer in April 2011 to discuss the role of physical activity on cancer survival and the methodology to develop multicentre randomized intervention trials, including the type of physical activity to implement and its association with nutritional recommendations. The authors discuss the beneficial effect of physical activity on cancer survival with a main focus on breast cancer and report the conclusions from this workshop.

Keywords: cancer; nutrition; physical activity; prevention.

Publication types

  • Congress

MeSH terms

  • Breast Neoplasms / mortality
  • Breast Neoplasms / physiopathology
  • Breast Neoplasms / psychology
  • Breast Neoplasms / rehabilitation
  • Cause of Death
  • Cohort Studies
  • Comorbidity
  • Cytokines / metabolism
  • Exercise
  • Exercise Therapy
  • Fatigue / etiology
  • Fatigue / prevention & control
  • Female
  • Follow-Up Studies
  • Gonadal Steroid Hormones / metabolism
  • Humans
  • Intercellular Signaling Peptides and Proteins / metabolism
  • Meta-Analysis as Topic
  • Models, Biological
  • Motor Activity*
  • Multicenter Studies as Topic / statistics & numerical data
  • Neoplasms / mortality
  • Neoplasms / psychology
  • Neoplasms / rehabilitation*
  • Obesity / epidemiology
  • Obesity / physiopathology
  • Obesity / therapy
  • Prospective Studies
  • Quality of Life
  • Randomized Controlled Trials as Topic / statistics & numerical data
  • Survivors / psychology

Substances

  • Cytokines
  • Gonadal Steroid Hormones
  • Intercellular Signaling Peptides and Proteins