Chronobiology and nutrition

Neuroscience. 2013 Dec 3:253:78-88. doi: 10.1016/j.neuroscience.2013.08.049. Epub 2013 Sep 3.


Numerous long-term studies have investigated the circadian clock system in mammals, which organizes physiological functions, including metabolism, digestion, and absorption of food, and energy expenditure. Food or nutrition can be a synchronizer for the circadian clock systems, as potent as the external light-dark signal can be. Recent studies have investigated different kinds of food, frequency of consumption, and time of consumption for optimizing body clock and ensuring healthy habits. In this review, we discuss recent studies investigating chronobiology and nutrition, and then summarize available information as "Chrono-nutrition" for the development of a new standardized research strategy.

Keywords: AMPK; DMH; FAA; FEO; Glut2; KO; LHA; NAD; PARP-1; Poly(ADP-ribose) polymerase 1; SCN; Sglt1; WT; ZT; Zeitgeber time; adenosine monophosphate-activated protein kinase; circadian rhythm; clock; dorsomedial hypothalamus; food anticipatory activity; food entrainable oscillator; glucose transporter 2; knock-out; lateral hypothalamus; liver; nNOS; neuronal nitric oxide synthase; nicotinamide adenine dinucleotide; obesity; period 2; sodium/glucose cotransporter 1; suprachiasmatic nucleus; wild type.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Chronobiology Phenomena*
  • Feeding Behavior / physiology*
  • Humans
  • Nutritional Physiological Phenomena*