Abstract
DRESS syndrome is an idiosyncratic reaction to drugs, which can occur in both adults and children. To date there is no agreed upon criteria for its diagnosis; there is even less consensus on its management. We report the case of a 14- year-old boy with carbamazepine induced DRESS syndrome, predominantly involving the liver. He responded rapidly to high dose pulsed intravenous corticosteroids.
MeSH terms
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Adolescent
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Anti-Inflammatory Agents / administration & dosage
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Anti-Inflammatory Agents / therapeutic use*
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Anticonvulsants / adverse effects*
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Anticonvulsants / therapeutic use
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Brain Injuries / complications
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Carbamazepine / adverse effects*
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Carbamazepine / therapeutic use
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Drug Hypersensitivity Syndrome / drug therapy
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Drug Hypersensitivity Syndrome / etiology*
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Drug Hypersensitivity Syndrome / pathology
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Drug Therapy, Combination
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Emollients / therapeutic use*
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Fluocinolone Acetonide / administration & dosage
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Fluocinolone Acetonide / therapeutic use*
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Hepatomegaly / chemically induced
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Hepatomegaly / drug therapy
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Humans
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Male
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Methylprednisolone / administration & dosage
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Methylprednisolone / therapeutic use*
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Mineral Oil / therapeutic use*
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Pulse Therapy, Drug
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Seizures / drug therapy
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Seizures / etiology
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Skin / pathology
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Ursodeoxycholic Acid / therapeutic use*
Substances
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Anti-Inflammatory Agents
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Anticonvulsants
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Emollients
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Fluocinolone Acetonide
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Carbamazepine
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Ursodeoxycholic Acid
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Mineral Oil
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Methylprednisolone