Adverse effects of depression on glycemic control and health outcomes in people with diabetes: a review

Endocrinol Metab Clin North Am. 2013 Sep;42(3):529-44. doi: 10.1016/j.ecl.2013.05.002.


In the past decades, important advances have been achieved in the psychological aspects of diabetes. This article reviews the associations between diabetes, depression, and adverse health outcomes. The article provides an update on the literature regarding the prevalence of depression in diabetes, discusses the impact of depression on diabetes self-care and glycemic control in people with diabetes, and summarizes the results of longitudinal studies that have investigated depression as a risk factor for adverse health outcomes.

Keywords: Cardiovascular disease; Depression; Microvascular disease; Mortality; Review; Type 1 diabetes; Type 2 diabetes.

Publication types

  • Review

MeSH terms

  • Depression / metabolism*
  • Diabetes Complications / metabolism
  • Diabetes Complications / psychology
  • Diabetes Mellitus, Type 1 / metabolism
  • Diabetes Mellitus, Type 1 / psychology*
  • Diabetes Mellitus, Type 2 / metabolism
  • Diabetes Mellitus, Type 2 / psychology*
  • Female
  • Humans
  • Longitudinal Studies
  • Male
  • Prevalence