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, 7 (3), 322-6

Tapentadol Hydrochloride: A Novel Analgesic


Tapentadol Hydrochloride: A Novel Analgesic

Dewan Roshan Singh et al. Saudi J Anaesth.


Tapentadol is a novel, centrally acting analgesic with dual mechanism of action, combining mu-opioid receptor agonism with noradrenaline reuptake inhibition in the same molecule. It has an improved side effect profile when compared to opioids and nonsteroidal anti-inflammatory drugs. The dual mechanism of action makes Tapentadol a useful analgesic to treat acute, chronic, and neuropathic pain.

Keywords: Nonsteroidal anti-inflammatory drugs; opioids; tapentadol hydrochloride.

Conflict of interest statement

Conflict of Interest: None declared


Figure 1
Figure 1
Chemical structure of Tapentadol

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