Stereoselective synthesis of five-membered spirooxindoles through Tomita zipper cyclization

D B Ramachary; Chintalapudi Venkaiah; Patoju M Krishna

doi:10.1021/ol4020305

Stereoselective synthesis of five-membered spirooxindoles through Tomita zipper cyclization

Org Lett. 2013 Sep 20;15(18):4714-7. doi: 10.1021/ol4020305. Epub 2013 Sep 9.

Authors

D B Ramachary¹, Chintalapudi Venkaiah, Patoju M Krishna

Affiliation

¹ Catalysis Laboratory, School of Chemistry, University of Hyderabad , Central University (PO), Hyderabad 500 046, India.

PMID: 24015947
DOI: 10.1021/ol4020305

Abstract

Functionalized five-membered spirooxindoles were furnished in good yields and excellent stereoselectivities by using an effective Tomita zipper cyclization (TZC) reaction through organophosphine catalysis.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Catalysis
Combinatorial Chemistry Techniques
Cyclization
Indoles / chemical synthesis*
Indoles / chemistry
Molecular Structure
Spiro Compounds / chemical synthesis*
Spiro Compounds / chemistry
Stereoisomerism

Substances

Indoles
Spiro Compounds