Human papillomavirus vaccines in Picardy, France: coverage and correlation with socioeconomic factors

Abstract

Background: In France, the human papillomavirus vaccine is routinely recommended for 14-year-old females and a "catch-up" vaccination should be offered to female adolescents who are between 15 and 23 years of age. Currently, few studies are available on the coverage rates in France. The aim of this study was to evaluate the coverage of the human papillomavirus vaccine and compliance with the vaccination scheme in Picardy, between 2009 and 2010, and to analyze the socioeconomic factors possibly influencing this coverage.

Methods: We selected a female population that was affiliated with the national health insurance organization, living in the Picardy region of France, and aged between 14 and 23 years on 31st December 2010.

Results: The coverage rate in the study population with at least one dose of vaccine was 16.8%. A complete vaccination scheme (three doses) was observed in less than 38.9% of them, so only 6.5% of this population had received the complete vaccination. Higher rates of coverage and compliance were observed in girls 14 years of age (65.5%) and if the prescriber was a gynecologist or pediatrician (respectively, 44.7% and 48.1%). There is a negative correlation between coverage and compliance and the percentage of single-parent families and immigrant families by canton area of Picardy. The economic cost of an inappropriate scheme was 1.3 million euros for Picardy in 2009.

Conclusion: Coverage and compliance rates of human papillomavirus vaccines in Picardy appear to be low. This study suggests that health authorities in Picardy should provide communication and action campaigns to improve these results.

Keywords: Adolescentes; Adolescents; Facteurs socioéconomiques; HPV; Human papillomavirus; Picardie; Picardy; Socioeconomic factors; Vaccination.