Explicet: graphical user interface software for metadata-driven management, analysis and visualization of microbiome data

Bioinformatics. 2013 Dec 1;29(23):3100-1. doi: 10.1093/bioinformatics/btt526. Epub 2013 Sep 10.


Studies of the human microbiome, and microbial community ecology in general, have blossomed of late and are now a burgeoning source of exciting research findings. Along with the advent of next-generation sequencing platforms, which have dramatically increased the scope of microbiome-related projects, several high-performance sequence analysis pipelines (e.g. QIIME, MOTHUR, VAMPS) are now available to investigators for microbiome analysis. The subject of our manuscript, the graphical user interface-based Explicet software package, fills a previously unmet need for a robust, yet intuitive means of integrating the outputs of the software pipelines with user-specified metadata and then visualizing the combined data.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Computational Biology
  • Computer Graphics*
  • Database Management Systems*
  • High-Throughput Nucleotide Sequencing
  • Humans
  • Metagenome
  • Microbiota / genetics*
  • Sequence Analysis, DNA
  • Software*
  • User-Computer Interface*