Presentation and management of trapped neutrophil syndrome (TNS) in UK Border collies

J Small Anim Pract. 2014 Jan;55(1):57-60. doi: 10.1111/jsap.12134. Epub 2013 Sep 13.

Abstract

Three UK bred Border collie puppies were presented for investigation of pyrexia and severe lameness with associated joint swelling. Investigations revealed neutropenia, radiographic findings suggesting metaphyseal osteopathy, and polyarthritis and all dogs were subsequently confirmed with trapped neutrophil syndrome. Clinical improvement was seen after treatment with prednisolone and antibiotics and the dogs all survived to adulthood with a good short- to medium-term outcome. Trapped neutrophil syndrome is an important differential diagnosis for young Border collie dogs in the UK presenting with pyrexia, neutropenia and musculoskeletal signs.

Publication types

  • Case Reports

MeSH terms

  • Animals
  • Anti-Bacterial Agents / therapeutic use
  • Arthritis / diagnosis
  • Arthritis / drug therapy
  • Arthritis / genetics
  • Arthritis / veterinary
  • Dog Diseases / diagnosis*
  • Dog Diseases / drug therapy
  • Dog Diseases / genetics
  • Dogs
  • Female
  • Fever / diagnosis
  • Fever / drug therapy
  • Fever / genetics
  • Fever / veterinary
  • Leukocyte Count / veterinary
  • Male
  • Neutropenia / diagnosis
  • Neutropenia / drug therapy
  • Neutropenia / veterinary*
  • Neutrophils
  • Prednisolone / therapeutic use
  • Syndrome
  • United Kingdom

Substances

  • Anti-Bacterial Agents
  • Prednisolone