Accelerating the controlled synthesis of metal-organic frameworks by a microfluidic approach: a nanoliter continuous reactor

ACS Appl Mater Interfaces. 2013 Oct 9;5(19):9405-10. doi: 10.1021/am4029872. Epub 2013 Sep 26.


Segmented microfluidics was applied to the ultrafast crystallization of dicarboxylate based MIL-88B type metal-organic frameworks (MOFs; Fe-MIL-88B-NH2, Fe-MIL-88B, and Fe-MIL-88B-Br). Particular attention was paid to the influence of the temperature, residence time, and slug volume on the size and crystal size distribution of the MOFs. Average sizes in the 90-900 nm range with relatively narrow crystal size distributions were obtained with residence times as short as 20 s depending on the MOF type and synthesis conditions.

Publication types

  • Research Support, Non-U.S. Gov't