IntOGen-mutations identifies cancer drivers across tumor types

Nat Methods. 2013 Nov;10(11):1081-2. doi: 10.1038/nmeth.2642. Epub 2013 Sep 15.


The IntOGen-mutations platform ( summarizes somatic mutations, genes and pathways involved in tumorigenesis. It identifies and visualizes cancer drivers, analyzing 4,623 exomes from 13 cancer sites. It provides support to cancer researchers, aids the identification of drivers across tumor cohorts and helps rank mutations for better clinical decision-making.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Exome
  • Humans
  • Mutation*
  • Neoplasms / classification
  • Neoplasms / genetics*
  • Neoplasms / pathology