A tandem synthesis of functionalized azet-2(1H)-ones and azet-2(1H)-thiones

Mol Divers. 2013 Nov;17(4):809-15. doi: 10.1007/s11030-013-9479-1. Epub 2013 Sep 17.

Abstract

Highly functionalized azet-2(1H)-ones and azet-2(1H)-thiones are obtained via a copper-catalyzed tandem reaction of readily available terminal alkynes, sulfonyl azides, and heterocummulenes in moderate to good yields.

MeSH terms

  • Catalysis
  • Combinatorial Chemistry Techniques*
  • Copper
  • Thiones / chemical synthesis*
  • Thiones / chemistry

Substances

  • Thiones
  • Copper