The chinese american eye study: design and methods

Ophthalmic Epidemiol. 2013 Dec;20(6):335-47. doi: 10.3109/09286586.2013.823505. Epub 2013 Sep 18.


Purpose: To summarize the study design, operational strategies and procedures of the Chinese American Eye Study (CHES), a population-based assessment of the prevalence of visual impairment, ocular disease, and visual functioning in Chinese Americans.

Methods: This population-based, cross-sectional study included 4570 Chinese participants aged 50 years and older, residing in the city of Monterey Park, California. Each eligible participant completed a detailed interview and eye examination. The interview included an assessment of demographic, behavioral and ocular risk factors and health-related and vision-related quality of life. The eye examination included measurements of visual acuity, intraocular pressure, visual fields, fundus and optic disc photography, a detailed anterior and posterior segment examination, and measurements of blood pressure, glycosylated hemoglobin levels, and blood glucose levels.

Results: The objectives of the CHES are to obtain prevalence estimates of visual impairment, refractive error, diabetic retinopathy, open-angle and angle-closure glaucoma, lens opacities, and age-related macular degeneration in Chinese Americans. In addition, outcomes include effect estimates for risk factors associated with eye diseases. Lastly, CHES will investigate the genetic determinants of myopia and glaucoma.

Conclusion: The CHES will provide information about the prevalence and risk factors of ocular diseases in one of the fastest growing minority groups in the United States.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Asian
  • Blood Glucose / metabolism
  • Blood Pressure / physiology
  • California / epidemiology
  • China / ethnology
  • Cross-Sectional Studies
  • Eye Diseases / ethnology*
  • Female
  • Glycated Hemoglobin / metabolism
  • Humans
  • Intraocular Pressure / physiology
  • Male
  • Middle Aged
  • Minority Groups / statistics & numerical data
  • Prevalence
  • Quality of Life / psychology
  • Research Design*
  • Risk Factors
  • Vision, Ocular / physiology
  • Visual Acuity / physiology
  • Visually Impaired Persons / statistics & numerical data*


  • Blood Glucose
  • Glycated Hemoglobin A
  • hemoglobin A1c protein, human