Antioxidant supplements to prevent mortality

JAMA. 2013 Sep 18;310(11):1178-9. doi: 10.1001/jama.2013.277028.


Clinical question: Are antioxidant supplements associated with higher or lower all-cause mortality?

Bottom line: Antioxidant supplements are not associated with lower all-cause mortality. Beta carotene, vitamin E, and higher doses of vitamin A may be associated with higher all-cause mortality.

Publication types

  • Comment

MeSH terms

  • Animals
  • Antioxidants / metabolism*
  • Humans
  • Oxidants / metabolism*
  • Oxidative Stress / physiology*


  • Antioxidants
  • Oxidants