Peptidylarginine deiminase in rat and mouse hemopoietic cells

Experientia. 1990 Jan 15;46(1):72-4. doi: 10.1007/BF01955420.

Abstract

Peptidylarginine (protein-L-arginine) deiminase activities have been demonstrated in extracts of rat and mouse peritoneal macrophages, bone marrow cells, splenic adherent cells, neutrophils, and mouse monocyte/macrophage cell lines. The enzyme in these cells is indistinguishable from the skeletal muscle enzyme with respect to immunochemical properties.

MeSH terms

  • Ammonia / metabolism
  • Animals
  • Arginine / analogs & derivatives
  • Arginine / metabolism
  • Blotting, Western
  • Bone Marrow / enzymology
  • Bone Marrow Cells*
  • Citrulline / metabolism
  • Female
  • Hydrolases / metabolism*
  • Immunosorbent Techniques
  • Macrophages / enzymology*
  • Mice
  • Mice, Inbred C57BL
  • Monocytes / enzymology*
  • Neutrophils / enzymology*
  • Peritoneal Cavity / cytology
  • Protein-Arginine Deiminase Type 4
  • Protein-Arginine Deiminases
  • Rats
  • Rats, Inbred Strains
  • Spleen / cytology*
  • Spleen / enzymology

Substances

  • Citrulline
  • Ammonia
  • Arginine
  • benzoylarginine ethyl ester
  • Hydrolases
  • Protein-Arginine Deiminase Type 4
  • Protein-Arginine Deiminases
  • peptidylarginine deiminase 4, mouse