New clonal strain of Candida auris, Delhi, India

Emerg Infect Dis. 2013 Oct;19(10):1670-3. doi: 10.3201/eid1910.130393.

Abstract

A new clonal strain of Candida auris is an emerging etiologic agent of fungemia in Delhi, India. In 12 patients in 2 hospitals, it was resistant to fluconazole and genotypically distinct from isolates from South Korea and Japan, as revealed by M13 and amplified fragment length polymorphism typing.

Keywords: AFLP; Candida auris; India; M13 fingerprinting; antifungal susceptibility; fungemia; fungi; parasitic diseases.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Antifungal Agents / pharmacology
  • Antifungal Agents / therapeutic use
  • Candida / classification
  • Candida / genetics*
  • Candida / isolation & purification
  • Candidiasis / drug therapy
  • Candidiasis / microbiology*
  • Candidiasis / mortality
  • Child
  • DNA, Fungal / genetics
  • DNA, Ribosomal Spacer / genetics
  • Drug Resistance, Fungal
  • Female
  • Fluconazole / pharmacology
  • Fluconazole / therapeutic use
  • Fungemia / drug therapy
  • Fungemia / microbiology*
  • Fungemia / mortality
  • Humans
  • India
  • Infant
  • Infant, Newborn
  • Male
  • Microbial Sensitivity Tests
  • Middle Aged
  • Multilocus Sequence Typing
  • Phylogeny
  • Polymorphism, Restriction Fragment Length
  • Treatment Outcome

Substances

  • Antifungal Agents
  • DNA, Fungal
  • DNA, Ribosomal Spacer
  • Fluconazole