I2-SDS-H2O System: A highly Efficient Dual Catalytic Green System for Deprotection of Imines and in Situ Preparation of Bis(indolyl)alkanes from Indoles in Water

Parasa Hazarika; Pallab Pahari; Manash Jyoti Borah; Dilip Konwar

doi:10.5402/2012/635835

I2-SDS-H2O System: A highly Efficient Dual Catalytic Green System for Deprotection of Imines and in Situ Preparation of Bis(indolyl)alkanes from Indoles in Water

ISRN Org Chem. 2012 Aug 27:2012:635835. doi: 10.5402/2012/635835. eCollection 2012.

Authors

Parasa Hazarika¹, Pallab Pahari, Manash Jyoti Borah, Dilip Konwar

Affiliation

¹ Department of Chemistry, Jorhat Institute of Science and Technology, Assam Jorhat 785010, India ; Synthetic Organic Chemistry Division, North East Institute of Science and Technology, Assam Jorhat 785006, India.

Abstract

A novel catalytic system consisting of I2-SDS-H2O has been developed which cleaves 2,3-diaza-1,3-butadiene, 1-aza-1,3-butadienes, oximes and in presence of indoles in the medium uses the corresponding aldehyde products to produce bis(indolyl)alkanes in situ. This one pot simple and mild dual catalytic system works in water at room temperature under neutral conditions.