Sensorimotor polyneuropathy after hexavalent vaccination

Scand J Infect Dis. 2014 Jan;46(1):66-8. doi: 10.3109/00365548.2013.831183. Epub 2013 Sep 20.

Abstract

New vaccines in infants are generally well tolerated and serious adverse events are rare. We present a patient who developed severe sensorimotor polyneuropathy 2 weeks after the first immunization with hexavalent routine vaccine (INFANRIX hexa). Through intense physiotherapy the infant made a complete recovery.

Publication types

  • Case Reports

MeSH terms

  • Diphtheria-Tetanus-Pertussis Vaccine / administration & dosage
  • Diphtheria-Tetanus-Pertussis Vaccine / adverse effects*
  • Haemophilus Vaccines / administration & dosage
  • Haemophilus Vaccines / adverse effects*
  • Hepatitis B Vaccines / administration & dosage
  • Hepatitis B Vaccines / adverse effects*
  • Humans
  • Infant
  • Male
  • Physical Therapy Modalities
  • Poliovirus Vaccine, Inactivated / administration & dosage
  • Poliovirus Vaccine, Inactivated / adverse effects*
  • Polyneuropathies / chemically induced*
  • Polyneuropathies / diagnosis
  • Polyneuropathies / pathology
  • Treatment Outcome
  • Vaccination / adverse effects*
  • Vaccination / methods
  • Vaccines, Combined / administration & dosage
  • Vaccines, Combined / adverse effects

Substances

  • Diphtheria-Tetanus-Pertussis Vaccine
  • Haemophilus Vaccines
  • Hepatitis B Vaccines
  • Poliovirus Vaccine, Inactivated
  • Vaccines, Combined
  • diphtheria-tetanus-acellular pertussis-inactivated poliovirus-Haemophilus influenzae b conjugate-hepatitis B vaccine