Double blind comparison of transdermal hyoscine and placebo for the prevention of postoperative nausea

E M Koski; M A Mattila; D Knapik; T Toivanen; H Ruusukallio; P Andersson; Y Freudenthal

doi:10.1093/bja/64.1.16

Double blind comparison of transdermal hyoscine and placebo for the prevention of postoperative nausea

Br J Anaesth. 1990 Jan;64(1):16-20. doi: 10.1093/bja/64.1.16.

Authors

E M Koski¹, M A Mattila, D Knapik, T Toivanen, H Ruusukallio, P Andersson, Y Freudenthal

Affiliation

¹ Kuopio University Central Hospital, Finland.

PMID: 2405893
DOI: 10.1093/bja/64.1.16

Abstract

Transdermal hyoscine (Scopoderm, Ciba-Geigy) has been compared with placebo in 283 female patients. The hyoscine patch had no significant effect on postoperative nausea or vomiting. In contrast with earlier studies, there was no correlation between previous experiences of nausea (motion, pregnancy or surgery related) and nausea caused by the surgery or anaesthetic in this study. No correlation was found between nausea or vomiting and the type of operation.

Publication types

Clinical Trial
Comparative Study
Randomized Controlled Trial

MeSH terms

Administration, Cutaneous
Adolescent
Adult
Aged
Double-Blind Method
Female
Humans
Middle Aged
Nausea / prevention & control*
Postoperative Complications / prevention & control*
Randomized Controlled Trials as Topic
Scopolamine / administration & dosage
Scopolamine / adverse effects
Scopolamine / therapeutic use*
Vomiting / prevention & control

Substances

Scopolamine