Successful use of a military-grade haemostatic agent for a major head and neck bleed

J Laryngol Otol. 2013 Oct;127(10):1031-3. doi: 10.1017/S0022215113002089. Epub 2013 Sep 23.

Abstract

Background: Major haemorrhage is a catastrophic complication occurring in 3-4 per cent of head and neck cancer patients. Massive haemorrhage also causes 50 per cent of preventable deaths in combat situations. There has been a surge of interest in the development of effective haemostatic products in the military, with chitosan being one such product.

Case report: A 48-year-old lady presented with a life-threatening head and neck bleed. She was known to have a malignant peripheral nerve sheath sarcoma originating from the left parapharyngeal space. Bleeding was successfully controlled with the application of Celox™ granules, a chitosan-based product currently used in the military.

Conclusion: This paper describes the first known use of a military haemostatic agent to control a malignant head and neck bleed. Celox granules can be poured directly onto a wound to enhance haemorrhage control. The suggested mechanism of action and reports of current uses of haemostatic agents are described.

Publication types

  • Case Reports

MeSH terms

  • Biopolymers / therapeutic use
  • Chitosan / therapeutic use
  • Female
  • Head and Neck Neoplasms / complications
  • Hemorrhage / drug therapy*
  • Hemorrhage / etiology
  • Hemostatic Techniques*
  • Hemostatics / therapeutic use*
  • Humans
  • Middle Aged
  • Military Personnel
  • Nerve Sheath Neoplasms / complications*

Substances

  • Biopolymers
  • Celox
  • Hemostatics
  • Chitosan