A comparison of percutaneous needle fasciotomy and collagenase injection for dupuytren disease

Abstract

Purpose: To compare percutaneous needle fasciotomy (PNF) with collagenase injection in the treatment of Dupuytren contracture.

Methods: A retrospective review was performed for patients with Dupuytren disease treated with PNF or collagenase. Range of motion, patient satisfaction, and complications were recorded.

Results: There were 29 patients in the collagenase group with mean baseline contractures of 40° for 22 affected metacarpophalangeal joints and 50° for 12 affected proximal interphalangeal joints. The PNF group was composed of 30 patients with mean baseline contractures of 37° for 32 affected metacarpophalangeal joints and 41° for 18 affected proximal interphalangeal joints. All patients were observed for a minimum of 3 months. Clinical success (reduction of contracture within 0° to 5° of normal) was accomplished in 35 of 50 joints (67%) in the PNF group and in 19 of 34 joints (56%) in the collagenase group. Patient satisfaction was similar between groups. Only minor complications were observed, including skin tears, ecchymosis, edema, pruritus, and lymphadenopathy.

Conclusions: In the short term, both PNF and collagenase have similar clinical outcomes and patient satisfaction.

Type of study/level of evidence: Therapeutic III.

Keywords: Dupuytren; collagenase; percutaneous needle fasciotomy.