Purpose: To present a case of a full-thickness macular hole closure in a patient with Behcet uveitis.
Design: A 23-year-old-male patient with Behcet Disease had clinically inactive uveitis with topical steroids, oral azathiopurine and cyclosporine until he developed a retinal infiltrate in the left eye which evolved into a full-thickness macular hole during the follow-up.
Methods: Strict control of inflammation and subsequent vitrectomy was planned. Meanwhile another attack of panuveitis developed in the left eye and subcutaneous Interferon alfa-2b interferon treatment was initiated.
Results: After 2 months, the patient was clinically inactive with complete closure of the macular hole.
Conclusions: Strict control of inflammation may result in closure of the macular hole and avoid the need for vitrectomy.