Bilateral optic neuritis--the only ocular finding in a case of subacute sclerosing panencephalitis

Ocul Immunol Inflamm. 2014 Feb;22(1):82-5. doi: 10.3109/09273948.2013.829108. Epub 2013 Sep 24.


Subacute sclerosing panencephalitis is a rare disease of central nervous system caused by defective measles virus. Chorioretinitis with macular involvement is the mostly observed ocular finding in the disease. Other reported ocular findings in the disease are cortical blindness, hemianopsia, nystagmus, extraocular muscle paresis and optic atrophy. We present a rare case of subacute sclerosing panencephalitis with isolated bilateral optic neuritis as the only ocular finding without macular involvement.

Publication types

  • Case Reports

MeSH terms

  • Anticonvulsants / therapeutic use
  • Antiviral Agents / therapeutic use
  • Carbamazepine / therapeutic use
  • Child
  • Drug Therapy, Combination
  • Electroencephalography
  • Female
  • Humans
  • Inosine Pranobex / therapeutic use
  • Magnetic Resonance Imaging
  • Optic Neuritis / diagnosis
  • Optic Neuritis / etiology*
  • Subacute Sclerosing Panencephalitis / complications*
  • Subacute Sclerosing Panencephalitis / diagnosis
  • Subacute Sclerosing Panencephalitis / drug therapy


  • Anticonvulsants
  • Antiviral Agents
  • Carbamazepine
  • Inosine Pranobex