Looming animate and inanimate threats: the response of the amygdala and periaqueductal gray

Soc Neurosci. 2013;8(6):621-30. doi: 10.1080/17470919.2013.839480. Epub 2013 Sep 25.

Abstract

Looming stimuli are processed as threatening and activate basic neural defense systems. However, it is unclear how animacy information modulates this response. Participants (N = 25) viewed threatening or neutral images that were either animate (animals) or inanimate (objects) and which either approached (loomed) or receded from the participant. The amygdala was responsive to emotional, animacy, and looming information (particularly to looming threats and looming animate stimuli). Periaqueductal gray was also sensitive to emotional information and particularly responsive to looming threats. The data are interpreted within category-specific models of the amygdala and temporal cortex.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, N.I.H., Intramural

MeSH terms

  • Adult
  • Amygdala / physiology*
  • Animals
  • Behavior / physiology*
  • Brain Mapping*
  • Fear / physiology*
  • Female
  • Humans
  • Image Processing, Computer-Assisted
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Periaqueductal Gray / physiology*
  • Photic Stimulation
  • Young Adult