Quinine-induced hearing loss

ORL J Otorhinolaryngol Relat Spec. 1990;52(1):65-8. doi: 10.1159/000276106.


Sensorineural hearing loss due to quinine therapy for malaria has frequently been mentioned in the literature but has not been a subject of research during the last decades. The global spreading of chloroquine-resistant falciparum malaria brings about an increasing use of quinine. The ototoxicity of quinine can accurately be studied with ultrahigh frequency audiometry (up to 20 kHz). The case of a 29-year-old man suffering from falciparum malaria disease who got a reversible hearing loss from quinine therapy is presented.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Animals
  • Audiometry / methods
  • Hearing Loss, Sensorineural / chemically induced*
  • Hearing Loss, Sensorineural / diagnosis
  • Humans
  • Malaria / drug therapy*
  • Male
  • Plasmodium falciparum
  • Quinine / adverse effects*
  • Quinine / therapeutic use


  • Quinine