Lung involvement in systemic sclerosis

Rheum Dis Clin North Am. 1990 Feb;16(1):199-216.


The lungs are frequently affected in systemic sclerosis, and pulmonary disease may significantly influence morbidity and mortality. The clinical, radiographic, and physiologic features of scleroderma lung disease are discussed in this article, as are new approaches to the detection and study of interstitial pneumonitis. The pathogenesis of pulmonary fibrosis is discussed in the context of data derived from bronchoalveolar lavage studies. Pulmonary vascular disease and less common pulmonary features of systemic sclerosis are also discussed.

Publication types

  • Review

MeSH terms

  • Humans
  • Lung / blood supply
  • Lung Diseases / diagnosis
  • Lung Diseases / etiology*
  • Lung Diseases / pathology
  • Lung Diseases / physiopathology
  • Pulmonary Fibrosis / etiology
  • Respiratory Function Tests
  • Scleroderma, Systemic / complications*
  • Scleroderma, Systemic / pathology
  • Scleroderma, Systemic / physiopathology
  • Vascular Diseases / etiology