A review of current imaging methods used in stroke research

Neurol Res. 2013 Dec;35(10):1092-102. doi: 10.1179/1743132813Y.0000000250. Epub 2013 Aug 16.


Stroke is a serious healthcare problem with high mortality and long-term disability. However, to date, our ability to prevent and cure stroke remains limited. One important goal in stroke research is to identify the extent and location of lesion for treatment. In addition, accurately differentiating salvageable tissue from infarct and evaluating therapeutic efficacies are indispensible. These objectives could potentially be met with the assistance of modern neuroimaging techniques. This paper reviews current imaging methods commonly used in ischemic stroke research. These methods include positron emission tomography, computed tomography, T1 MRI, T2 MRI, diffusion and perfusion MRI, diffusion tensor imaging, blood-brain barrier permeability MRI, pH-weighted MRI, and functional MRI.

Publication types

  • Review

MeSH terms

  • Animals
  • Cerebrovascular Circulation / physiology
  • Humans
  • Magnetic Resonance Imaging* / methods
  • Neuroimaging / methods
  • Positron-Emission Tomography* / methods
  • Stroke / diagnosis*
  • Stroke / physiopathology
  • Tomography, X-Ray Computed* / methods