Membrane traffic: the exocyst meets the cell cycle

Curr Biol. 2013 Sep 23;23(18):R838-40. doi: 10.1016/j.cub.2013.08.007.

Abstract

A new study describes a novel regulatory event that results in the inhibition of exocytic transport of a specific class of Golgi-derived vesicles during mitosis. The mechanism of inhibition is shown to involve direct phosphorylation of a subunit of the exocyst by a specific cyclin-dependent kinase complex.

Publication types

  • Comment

MeSH terms

  • Cell Cycle Checkpoints*
  • Exocytosis*
  • Membrane Proteins / metabolism*
  • Mitosis*
  • Saccharomyces cerevisiae / cytology*
  • Saccharomyces cerevisiae Proteins / metabolism*

Substances

  • Membrane Proteins
  • Saccharomyces cerevisiae Proteins