Langer-Giedion syndrome: the evolving imaging features in hands and beyond

Skeletal Radiol. 2014 Feb;43(2):251-5. doi: 10.1007/s00256-013-1726-0. Epub 2013 Sep 27.


Trichorhinophalangeal syndrome (TRP) is a group of rare genetic disorders with characteristic clinical and radiological features. In this case report we discuss the evolution of imaging features in hands in a Chinese boy diagnosed with TRP II (Langer-Giedion syndrome, LGS). This article ramifies the diagnostic value of serial hand radiograph in clinically suspected cases of TRP.

Publication types

  • Case Reports

MeSH terms

  • Child, Preschool
  • Hand Deformities, Congenital / diagnostic imaging*
  • Hand Deformities, Congenital / surgery*
  • Humans
  • Langer-Giedion Syndrome / diagnostic imaging*
  • Langer-Giedion Syndrome / surgery*
  • Male
  • Radiography
  • Thumb / abnormalities*
  • Thumb / surgery*
  • Treatment Outcome