WebGLORE: a web service for Grid LOgistic REgression
- PMID: 24072732
- PMCID: PMC3842761
- DOI: 10.1093/bioinformatics/btt559
WebGLORE: a web service for Grid LOgistic REgression
Abstract
WebGLORE is a free web service that enables privacy-preserving construction of a global logistic regression model from distributed datasets that are sensitive. It only transfers aggregated local statistics (from participants) through Hypertext Transfer Protocol Secure to a trusted server, where the global model is synthesized. WebGLORE seamlessly integrates AJAX, JAVA Applet/Servlet and PHP technologies to provide an easy-to-use web service for biomedical researchers to break down policy barriers during information exchange.
Availability and implementation: http://dbmi-engine.ucsd.edu/webglore3/. WebGLORE can be used under the terms of GNU general public license as published by the Free Software Foundation.
Figures
Similar articles
-
A collaborative framework for Distributed Privacy-Preserving Support Vector Machine learning.AMIA Annu Symp Proc. 2012;2012:1350-9. Epub 2012 Nov 3. AMIA Annu Symp Proc. 2012. PMID: 23304414 Free PMC article.
-
Grid Binary LOgistic REgression (GLORE): building shared models without sharing data.J Am Med Inform Assoc. 2012 Sep-Oct;19(5):758-64. doi: 10.1136/amiajnl-2012-000862. Epub 2012 Apr 17. J Am Med Inform Assoc. 2012. PMID: 22511014 Free PMC article.
-
Fair compute loads enabled by blockchain: sharing models by alternating client and server roles.J Am Med Inform Assoc. 2019 May 1;26(5):392-403. doi: 10.1093/jamia/ocy180. J Am Med Inform Assoc. 2019. PMID: 30892656 Free PMC article.
-
Supporting Regularized Logistic Regression Privately and Efficiently.PLoS One. 2016 Jun 6;11(6):e0156479. doi: 10.1371/journal.pone.0156479. eCollection 2016. PLoS One. 2016. PMID: 27271738 Free PMC article.
-
Extension of research data repository system to support direct compute access to biomedical datasets: enhancing Dataverse to support large datasets.Ann N Y Acad Sci. 2017 Jan;1387(1):95-104. doi: 10.1111/nyas.13272. Epub 2016 Nov 10. Ann N Y Acad Sci. 2017. PMID: 27862010 Free PMC article. Review.
Cited by
-
WebQuorumChain: A web framework for quorum-based health care model learning.Inform Med Unlocked. 2024;50:101590. doi: 10.1016/j.imu.2024.101590. Epub 2024 Oct 11. Inform Med Unlocked. 2024. PMID: 39483487 Free PMC article.
-
sPLINK: a hybrid federated tool as a robust alternative to meta-analysis in genome-wide association studies.Genome Biol. 2022 Jan 24;23(1):32. doi: 10.1186/s13059-021-02562-1. Genome Biol. 2022. PMID: 35073941 Free PMC article.
-
Web-Based Privacy-Preserving Multicenter Medical Data Analysis Tools Via Threshold Homomorphic Encryption: Design and Development Study.J Med Internet Res. 2020 Dec 8;22(12):e22555. doi: 10.2196/22555. J Med Internet Res. 2020. PMID: 33289676 Free PMC article.
-
The anatomy of a distributed predictive modeling framework: online learning, blockchain network, and consensus algorithm.JAMIA Open. 2020 Jul 6;3(2):201-208. doi: 10.1093/jamiaopen/ooaa017. eCollection 2020 Jul. JAMIA Open. 2020. PMID: 32734160 Free PMC article.
-
Privacy-preserving construction of generalized linear mixed model for biomedical computation.Bioinformatics. 2020 Jul 1;36(Suppl_1):i128-i135. doi: 10.1093/bioinformatics/btaa478. Bioinformatics. 2020. PMID: 32657380 Free PMC article.
References
-
- Fung BCM, et al. Privacy-preserving data publishing: a survey of recent developments. ACM Comput. Surv. 2010;42:1–53.
-
- Kennedy RL, et al. Early diagnosis of acute myocardial infarction using clinical and electrocardiographic data at presentation: derivation and evaluation of logistic regression models. Eur. Heart J. 1996;17:1181–1191. - PubMed
Publication types
MeSH terms
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources
