Abstract
The catalytic and asymmetric cycloaddition between 3-[1-(silyloxy)vinyl]indoles and electron-deficient olefins gave substituted hydrocarbazoles in up to 99% yield and 94% ee. This reaction was catalyzed by a novel chiral holmium(III) complex. Alkylation of the cycloadduct gave a tricyclic compound with four continuous chiral centers, one of which was a quaternary carbon.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alkenes / chemistry
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Carbazoles / chemical synthesis*
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Carbazoles / chemistry
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Catalysis
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Cyclization
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Holmium / chemistry*
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Indoles / chemistry*
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Molecular Structure
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Organometallic Compounds / chemistry*
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Silanes / chemistry*
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Stereoisomerism
Substances
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Alkenes
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Carbazoles
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Indoles
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Organometallic Compounds
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Silanes
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Holmium