Suppressor of cytokine signaling 3 expression is diminished in sinonasal tissues from patients with chronic rhinosinusitis with nasal polyps

J Allergy Clin Immunol. 2014 Jan;133(1):275-277.e1. doi: 10.1016/j.jaci.2013.08.015. Epub 2013 Sep 29.

Authors

Affiliations

¹ Division of Allergy-Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill.
² Department of Otolaryngology, Northwestern University Feinberg School of Medicine, Chicago, Ill.
³ Deparment of Pediatrics, University of Washington, Seattle, Wash.
⁴ Seattle Children's Hospital, Seattle, Wash.

^# Contributed equally.

No abstract available

Publication types

Letter
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Aged
Chronic Disease
Cytokines / immunology
Down-Regulation
Female
Humans
Male
Middle Aged
Nasal Polyps / complications
Nasal Polyps / immunology*
Paranasal Sinuses / immunology
Paranasal Sinuses / metabolism*
Phosphorylation
Rhinitis / complications
Rhinitis / immunology*
STAT3 Transcription Factor / metabolism
Sinusitis / complications
Sinusitis / immunology*
Suppressor of Cytokine Signaling 3 Protein
Suppressor of Cytokine Signaling Proteins / genetics
Suppressor of Cytokine Signaling Proteins / metabolism*
Th1-Th2 Balance
Young Adult

Substances

Cytokines
SOCS3 protein, human
STAT3 Transcription Factor
Suppressor of Cytokine Signaling 3 Protein
Suppressor of Cytokine Signaling Proteins

Grant support